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The 50 Best U.S. Cities for Businesses: Where Entrepreneurs Thrive

Starting a small business is both an exciting and challenging journey, and location plays a crucial role in determining success. Some cities offer better opportunities due to their economic climate, business-friendly policies, and vibrant entrepreneurial ecosystems.

In this post, we highlight the top 50 U.S. cities with the highest concentration of small businesses. Whether you’re an aspiring entrepreneur looking for the best place to launch your venture or a business owner seeking a thriving community to expand, this list will help you identify cities that foster innovation, networking, and growth.

From bustling metropolises like New York and Los Angeles to emerging hubs like Raleigh and Omaha, these cities are proving to be prime destinations for small business success. Let’s dive in!

RankMetropolitan AreaActive Small Business OwnersSmall Business Owners per 1,000 Population
1New York, NY814,81442.4
2Los Angeles, CA727,31055.0
3Miami, FL379,51061.5
4Houston, TX396,08356.1
5Dallas, TX329,14443.5
6Atlanta, GA317,27252.7
7Washington, DC270,98243.1
8Chicago, IL357,88237.8
9Philadelphia, PA197,21632.3
10Minneapolis, MN193,01553.0
11Seattle, WA175,67544.1
12Boston, MA223,37645.8
13Phoenix, AZ243,14249.1
14Denver, CO211,41071.2
15San Francisco, CA182,98238.7
16Orlando, FL151,17458.0
17Tampa, FL148,06446.3
18Raleigh, NC103,73174.6
19Kansas City, MO126,07858.5
20Portland, OR121,92848.9
21Charlotte, NC128,24448.6
22San Diego, CA127,48238.2
23Cincinnati, OH107,30948.3
24Columbus, OH104,55149.3
25Austin, TX99,02344.5
26Virginia Beach, VA94,74753.7
27St. Louis, MO67,63924.1
28Rochester, NY66,36562.0
29Oklahoma City, OK65,73446.7
30Pittsburgh, PA105,39445.5
31Nashville, TN111,84457.8
32Salt Lake City, UT55,67545.2
33Louisville, KY43,25334.2
34Richmond, VA52,01040.3
35Memphis, TN51,87938.6
36New Orleans, LA39,97731.5
37Omaha, NE39,99342.1
38Albuquerque, NM36,08439.5
39Greenville, SC30,71933.4
40Fresno, CA24,66524.7
41Tucson, AZ26,77725.6
42Hartford, CT42,66435.4
43Providence, RI59,31236.5
44Milwaukee, WI30,54819.4
45Jacksonville, FL56,35636.1
46Las Vegas, NV66,80129.5
47Buffalo, NY15,75114.0
48Birmingham, AL30,24427.7
49Bridgeport, CT77,58282.2
50Tulsa, OK60,39060.5

Note: These figures are based on data from AdvisorSmith’s analysis of U.S. cities with the most small business owners.

No matter which city you’re in, success in today’s competitive landscape requires smart marketing, strong branding, and a solid online presence. That’s where MyMarketingPro.com comes in.

Our platform is designed to help small businesses thrive with expert-driven marketing strategies, powerful digital tools, and personalized programs tailored to your industry. Whether you need website design, social media management, SEO optimization, or targeted ad campaigns, we’ve got the solutions to grow your brand and attract more customers.

Don’t navigate the challenges of entrepreneurship alone—partner with MyMarketingPro.com and let’s build something great together. Join today and take the first step toward small business success!

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